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Assignment of the disordered, proline-rich N-terminal domain of the tumour suppressor p53 protein using (1)H(N) and (1)H(α)-detected NMR measurements
Protein p53 is mostly known for playing a key role in tumour suppression, and mutations in the p53 gene are amongst the most frequent genomic events accompanying oncogenic transformation. Continuous research is conducted to target disordered proteins/protein regions for cancer therapy, for which ato...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630184/ https://www.ncbi.nlm.nih.gov/pubmed/37861971 http://dx.doi.org/10.1007/s12104-023-10160-4 |