The role of the FSGS disease gene product and nuclear pore protein NUP205 in regulating nuclear localization and activity of transcriptional regulators YAP and TAZ

Mutations in genes encoding nuclear pore proteins (NUPs) lead to the development of steroid-resistant nephrotic syndrome and focal segmental glomerulosclerosis (FSGS). However, the precise molecular mechanisms by which NUP dysfunction contributes to podocyte injury preceding FSGS remain unclear. The...

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Detalles Bibliográficos
Autores principales: Ester, Lioba, Cabrita, Inês, Ventzke, Michel, Kieckhöfer, Emilia, Christodoulou, Marita, Mandel, Amrei M, Diefenhardt, Paul, Fabretti, Francesca, Benzing, Thomas, Habbig, Sandra, Schermer, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630254/
https://www.ncbi.nlm.nih.gov/pubmed/37565816
http://dx.doi.org/10.1093/hmg/ddad135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630254/
https://www.ncbi.nlm.nih.gov/pubmed/37565816
http://dx.doi.org/10.1093/hmg/ddad135

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