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The role of the FSGS disease gene product and nuclear pore protein NUP205 in regulating nuclear localization and activity of transcriptional regulators YAP and TAZ
Mutations in genes encoding nuclear pore proteins (NUPs) lead to the development of steroid-resistant nephrotic syndrome and focal segmental glomerulosclerosis (FSGS). However, the precise molecular mechanisms by which NUP dysfunction contributes to podocyte injury preceding FSGS remain unclear. The...
Autores principales: | Ester, Lioba, Cabrita, Inês, Ventzke, Michel, Kieckhöfer, Emilia, Christodoulou, Marita, Mandel, Amrei M, Diefenhardt, Paul, Fabretti, Francesca, Benzing, Thomas, Habbig, Sandra, Schermer, Bernhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630254/ https://www.ncbi.nlm.nih.gov/pubmed/37565816 http://dx.doi.org/10.1093/hmg/ddad135 |
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