C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule

The precise modification or functionalization of the protein C-terminus is essential but full of challenges. Herein, a chemical approach to modify the C-terminus is developed by fusing a cysteine protease domain on the C-terminus of the protein of interest, which could achieve the non-enzymatic C-te...

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Detalles Bibliográficos
Autores principales: Zeng, Yue, Shi, Wei, Liu, Zhi, Xu, Hao, Liu, Liya, Hang, Jiaying, Wang, Yongqin, Lu, Mengru, Zhou, Wei, Huang, Wei, Tang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630284/
https://www.ncbi.nlm.nih.gov/pubmed/37935692
http://dx.doi.org/10.1038/s41467-023-42977-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630284/
https://www.ncbi.nlm.nih.gov/pubmed/37935692
http://dx.doi.org/10.1038/s41467-023-42977-x

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