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Fenofibrate alleviates insulin resistance by reducing tissue inflammation in obese ovariectomized mice

BACKGROUND: Fenofibrate is a hypolipidemic peroxisome proliferator-activated receptor α (PPARα) agonist used clinically to reduce hypercholesterolemia and hypertriglyceridemia. OBJECTIVE: We investigated the effects of fenofibrate on insulin resistance and tissue inflammation in a high-fat diet (HFD...

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Detalles Bibliográficos
Autores principales: Lee, Jungu, Jeon, Suyeon, Lee, Mijeong, Yoon, Michung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630285/
https://www.ncbi.nlm.nih.gov/pubmed/37935669
http://dx.doi.org/10.1038/s41387-023-00249-z