Cargando…

Fenofibrate alleviates insulin resistance by reducing tissue inflammation in obese ovariectomized mice

BACKGROUND: Fenofibrate is a hypolipidemic peroxisome proliferator-activated receptor α (PPARα) agonist used clinically to reduce hypercholesterolemia and hypertriglyceridemia. OBJECTIVE: We investigated the effects of fenofibrate on insulin resistance and tissue inflammation in a high-fat diet (HFD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jungu, Jeon, Suyeon, Lee, Mijeong, Yoon, Michung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630285/ https://www.ncbi.nlm.nih.gov/pubmed/37935669 http://dx.doi.org/10.1038/s41387-023-00249-z

Ejemplares similares

Fenofibrate Regulates Visceral Obesity and Nonalcoholic Steatohepatitis in Obese Female Ovariectomized C57BL/6J Mice
por: Shin, Yujin, et al.
Publicado: (2021)

Scutellaria baicalensis Alleviates Insulin Resistance in Diet-Induced Obese Mice by Modulating Inflammation
por: Na, Hyun-Young, et al.
Publicado: (2019)

Resveratrol alleviates obesity-associated podocyte injury in ovariectomized obese rats
por: Li, Bing, et al.
Publicado: (2020)

PPARα in Obesity: Sex Difference and Estrogen Involvement
por: Yoon, Michung
Publicado: (2010)

Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation
por: van Eijk, Marco, et al.
Publicado: (2009)

The Increase in Hepatic Uncoupling by Fenofibrate Contributes to a Decrease in Adipose Tissue in Obese Rats
por: Park, Mi-Kyoung, et al.
Publicado: (2007)

Lemon Balm Extract ALS-L1023 Regulates Obesity and Improves Insulin Sensitivity via Activation of Hepatic PPARα in High-Fat Diet-Fed Obese C57BL/6J Mice
por: Lee, Dongju, et al.
Publicado: (2020)

Medicines for the Treatment of Obesity
por: Shin, Soonshik, et al.
Publicado: (2021)

Fibrane the reduced derivative of fenofibrate
por: Kotheimer, Amanda E., et al.
Publicado: (2019)

Honokiol Improves Liver Steatosis in Ovariectomized Mice
por: Jeong, Yeon-Hui, et al.
Publicado: (2018)

Regulation of Obesity by Antiangiogenic Herbal Medicines
por: Shin, Soon Shik, et al.
Publicado: (2020)

Oxytocin reduces adipose tissue inflammation in obese mice
por: Szeto, Angela, et al.
Publicado: (2020)

Quercitrin Ameliorates Hyperlipidemia and Hepatic Steatosis in Ovariectomized Mice
por: Hur, Haeng Jeon, et al.
Publicado: (2020)

Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice
por: Kim, Jongkil, et al.
Publicado: (2016)

Interferon Tau Alleviates Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Macrophage Polarization
por: Ying, Wei, et al.
Publicado: (2014)

Alleviative Effect of Ficus formosana Extract on Peripheral Neuropathy in Ovariectomized Diabetic Mice
por: Ko, Chih-Yuan, et al.
Publicado: (2023)

Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice
por: Finch, Emily R., et al.
Publicado: (2020)

Dietary Eriodictyol Alleviates Adiposity, Hepatic Steatosis, Insulin Resistance, and Inflammation in Diet-Induced Obese Mice
por: Kwon, Eun-Young, et al.
Publicado: (2019)

Dietary Sinapic Acid Alleviates Adiposity and Inflammation in Diet-Induced Obese Mice
por: Yoon, Hye Jin, et al.
Publicado: (2022)

Post-Effects of Time-Restricted Feeding against Adipose Tissue Inflammation and Insulin Resistance in Obese Mice
por: Yun, Narae, et al.
Publicado: (2023)

Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice
por: Sasayama, Daimei, et al.
Publicado: (2017)

Modulation of the Gut Microbiota Structure with Probiotics and Isoflavone Alleviates Metabolic Disorder in Ovariectomized Mice
por: Chen, Qian, et al.
Publicado: (2021)

Can coenzyme Q10 alleviate the toxic effect of fenofibrate on skeletal muscle?
por: El-Bassouny, Dalia R., et al.
Publicado: (2023)

STAT4 Deficiency Reduces Obesity-Induced Insulin Resistance and Adipose Tissue Inflammation
por: Dobrian, Anca D., et al.
Publicado: (2013)

Deferoxamine Reduces Inflammation and Osteoclastogenesis in Avulsed Teeth
por: Lee, Ko Eun, et al.
Publicado: (2021)

Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway
por: Park, Ki-Sun, et al.
Publicado: (2022)

A Review of Currently Available Fenofibrate and Fenofibric Acid Formulations
por: Ling, Hua, et al.
Publicado: (2013)

Glucose‐dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance, but deteriorated bone loss in ovariectomized mice
por: Shimazu‐Kuwahara, Satoko, et al.
Publicado: (2018)

Differential susceptibility to obesity between male, female and ovariectomized female mice
por: Hong, Jina, et al.
Publicado: (2009)

Effect of Fenofibrate Medication on Renal Function
por: Kim, Sungjong, et al.
Publicado: (2017)

GPR30 Alleviates Pressure Overload-Induced Myocardial Hypertrophy in Ovariectomized Mice by Regulating Autophagy
por: Zhang, Shuaishuai, et al.
Publicado: (2023)

Fenofibrate treatment of rats with experimental autoimmune myocarditis by alleviating Treg/Th17 disorder
por: Cheng, Huilei, et al.
Publicado: (2016)

Estradiol treatment increases M2-like visceral adipose tissue macrophages in obese ovariectomized mice regardless of its anorectic action
por: Kim, Kyeong-dae, et al.
Publicado: (2022)

Fenofibrate Ameliorated Systemic and Retinal Inflammation and Modulated Gut Microbiota in High-Fat Diet-Induced Mice
por: Wang, Xue, et al.
Publicado: (2022)

Dietary Aloe Improves Insulin Sensitivity via the Suppression of Obesity-induced Inflammation in Obese Mice
por: Shin, Eunju, et al.
Publicado: (2011)

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice
por: White, Phillip J., et al.
Publicado: (2010)

Apocynin reduced doxycycline-induced acute liver injury in ovariectomized mice
por: Mitazaki, Satoru, et al.
Publicado: (2016)

Panax Ginseng alleviates thioacetamide-induced liver injury in ovariectomized rats: Crosstalk between inflammation and oxidative stress
por: Mostafa, Rasha E., et al.
Publicado: (2021)

Ramie leaf Extract Alleviates Bone Loss in Ovariectomized Rats—The Involvement of ROS and Its Associated Signalings
por: Lee, Geum-Hwa, et al.
Publicado: (2023)

PXR Ablation Alleviates Diet-Induced and Genetic Obesity and Insulin Resistance in Mice
por: He, Jinhan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_eq5ks1hdcn88d1k249q086alu5