Pyrroloquinoline quinone inhibits PCSK9-NLRP3 mediated pyroptosis of Leydig cells in obese mice

Abnormal lipid metabolism and chronic low-grade inflammation are the main traits of obesity. Especially, the molecular mechanism of concomitant deficiency in steroidogenesis-associated enzymes related to testosterone (T) synthesis of obesity dominated a decline in male fertility is still poorly unde...

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Detalles Bibliográficos
Autores principales: Wang, Jinyuan, Zhang, Shun, Hu, Linlin, Wang, Yan, Liu, Ke, Le, Jianghua, Tan, Yongpeng, Li, Tianlong, Xue, Haoxuan, Wei, Yanhong, Zhong, Ou, He, Junhui, Zi, Dan, Lei, Xin, Deng, Renhe, Luo, Yafei, Tang, Masong, Su, Mingxuan, Cao, Yichang, Liu, Qingyou, Tang, Zhihan, Lei, Xiaocan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630350/
https://www.ncbi.nlm.nih.gov/pubmed/37935689
http://dx.doi.org/10.1038/s41419-023-06162-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630350/
https://www.ncbi.nlm.nih.gov/pubmed/37935689
http://dx.doi.org/10.1038/s41419-023-06162-8

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