MePMe-seq: antibody-free simultaneous m(6)A and m(5)C mapping in mRNA by metabolic propargyl labeling and sequencing

Internal modifications of mRNA have emerged as widespread and versatile regulatory mechanism to control gene expression at the post-transcriptional level. Most of these modifications are methyl groups, making S-adenosyl-L-methionine (SAM) a central metabolic hub. Here we show that metabolic labeling...

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Detalles Bibliográficos
Autores principales: Hartstock, Katja, Kueck, Nadine A., Spacek, Petr, Ovcharenko, Anna, Hüwel, Sabine, Cornelissen, Nicolas V., Bollu, Amarnath, Dieterich, Christoph, Rentmeister, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630376/
https://www.ncbi.nlm.nih.gov/pubmed/37935679
http://dx.doi.org/10.1038/s41467-023-42832-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630376/
https://www.ncbi.nlm.nih.gov/pubmed/37935679
http://dx.doi.org/10.1038/s41467-023-42832-z

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