Spontaneous p53 activation in middle-aged C57BL/6 mice mitigates the lifespan-extending adaptive response induced by low-dose ionizing radiation

Understanding the biological effects of low-dose (<100 mGy) ionizing radiation (LDR) is technically challenging. We investigated age-dependent LDR effects using adaptive response experiments in young (7-to 12-week-old) and middle-aged (40-to 62-week-old) C57BL/6 mice. Compared with 3 Gy irradiati...

Descripción completa

Detalles Bibliográficos
Autores principales: Kohzaki, Masaoki, Suzuki, Keiji, Ootsuyama, Akira, Okazaki, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630390/
https://www.ncbi.nlm.nih.gov/pubmed/37935713
http://dx.doi.org/10.1038/s41514-023-00123-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630390/
https://www.ncbi.nlm.nih.gov/pubmed/37935713
http://dx.doi.org/10.1038/s41514-023-00123-3

Ejemplares similares