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Functional dissection of PRC1 subunits RYBP and YAF2 during neural differentiation of embryonic stem cells

Polycomb repressive complex 1 (PRC1) comprises two different complexes: CBX-containing canonical PRC1 (cPRC1) and RYBP/YAF2-containing variant PRC1 (vPRC1). RYBP-vPRC1 or YAF2-vPRC1 catalyzes H2AK119ub through a positive-feedback model; however, whether RYBP and YAF2 have different regulatory functi...

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Detalles Bibliográficos
Autores principales: Liu, Yanjiang, Hu, Gongcheng, Yang, Shengxiong, Yao, Mingze, Liu, Zicong, Yan, Chenghong, Wen, Yulin, Ping, Wangfang, Wang, Juehan, Song, Yawei, Dong, Xiaotao, Pan, Guangjin, Yao, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630410/
https://www.ncbi.nlm.nih.gov/pubmed/37935677
http://dx.doi.org/10.1038/s41467-023-42507-9