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ASMT determines gut microbiota and increases neurobehavioral adaptability to exercise in female mice

N-acetylserotonin O-methyltransferase (ASMT) is responsible for melatonin biosynthesis. The Asmt gene is located on the X chromosome, and its genetic polymorphism is associated with depression in humans. However, the underlying mechanism remains unclear. Here, we use CRISPR/Cas9 to delete 20 bp of e...

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Detalles Bibliográficos
Autores principales: Liu, Weina, Huang, Zhuochun, Zhang, Ye, Zhang, Sen, Cui, Zhiming, Liu, Wenbin, Li, Lingxia, Xia, Jie, Zou, Yong, Qi, Zhengtang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630421/
https://www.ncbi.nlm.nih.gov/pubmed/37935873
http://dx.doi.org/10.1038/s42003-023-05520-8