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Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus
Liquid-liquid phase separation (LLPS) has been thought to be the biophysical principle governing the assembly of the multiphase structures of nucleoli, the site of ribosomal biogenesis. Condensates assembled through LLPS increase their sizes to minimize the surface energy as far as their components...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630424/ https://www.ncbi.nlm.nih.gov/pubmed/37935838 http://dx.doi.org/10.1038/s42003-023-05519-1 |