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Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus

Liquid-liquid phase separation (LLPS) has been thought to be the biophysical principle governing the assembly of the multiphase structures of nucleoli, the site of ribosomal biogenesis. Condensates assembled through LLPS increase their sizes to minimize the surface energy as far as their components...

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Detalles Bibliográficos
Autores principales: Yamamoto, Tetsuya, Yamazaki, Tomohiro, Ninomiya, Kensuke, Hirose, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630424/
https://www.ncbi.nlm.nih.gov/pubmed/37935838
http://dx.doi.org/10.1038/s42003-023-05519-1