The tumor-enriched small molecule gambogic amide suppresses glioma by targeting WDR1-dependent cytoskeleton remodeling

Glioma is the most prevalent brain tumor, presenting with limited treatment options, while patients with malignant glioma and glioblastoma (GBM) have poor prognoses. The physical obstacle to drug delivery imposed by the blood‒brain barrier (BBB) and glioma stem cells (GSCs), which are widely recogni...

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Detalles Bibliográficos
Autores principales: Qu, Jiaorong, Qiu, Bojun, Zhang, Yuxin, Hu, Yan, Wang, Zhixing, Guan, Zhiang, Qin, Yiming, Sui, Tongtong, Wu, Fan, Li, Boyang, Han, Wei, Peng, Xiaozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630452/
https://www.ncbi.nlm.nih.gov/pubmed/37935665
http://dx.doi.org/10.1038/s41392-023-01666-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630452/
https://www.ncbi.nlm.nih.gov/pubmed/37935665
http://dx.doi.org/10.1038/s41392-023-01666-3

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