Venetoclax plus cyclophosphamide and topotecan in heavily pre-treated relapsed metastatic neuroblastoma: a single center case series

The prognosis of relapsed/refractory (R/R) neuroblastoma (NB) is dismal, calling for new therapeutic strategies. Venetoclax (VEN) is a highly selective, potent, orally bioavailable, BCL-2 inhibitor small-molecule that showed a synergistic effect with cyclophosphamide and topotecan (Cy-Topo) in murin...

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Detalles Bibliográficos
Autores principales: De Ioris, Maria Antonietta, Fabozzi, Francesco, Del Bufalo, Francesca, Del Baldo, Giada, Villani, Maria Felicia, Cefalo, Maria Giuseppina, Garganese, Maria Carmen, Stracuzzi, Alessandra, Tangari, Federica, Greco, Arturo Maria, Giovannoni, Isabella, Carta, Roberto, D’Andrea, Maria Luisa, Mastronuzzi, Angela, Locatelli, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630499/
https://www.ncbi.nlm.nih.gov/pubmed/37935707
http://dx.doi.org/10.1038/s41598-023-44993-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630499/
https://www.ncbi.nlm.nih.gov/pubmed/37935707
http://dx.doi.org/10.1038/s41598-023-44993-9

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