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Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans

Coronavirus spike glycoproteins presented on the virion surface mediate receptor binding, and membrane fusion during virus entry and constitute the primary target for vaccine and drug development. How the structure dynamics of the full-length spikes incorporated in viral lipid envelope correlates wi...

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Detalles Bibliográficos
Autores principales: Chmielewski, David, Wilson, Eric A., Pintilie, Grigore, Zhao, Peng, Chen, Muyuan, Schmid, Michael F., Simmons, Graham, Wells, Lance, Jin, Jing, Singharoy, Abhishek, Chiu, Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630519/
https://www.ncbi.nlm.nih.gov/pubmed/37935678
http://dx.doi.org/10.1038/s41467-023-42836-9