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Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans
Coronavirus spike glycoproteins presented on the virion surface mediate receptor binding, and membrane fusion during virus entry and constitute the primary target for vaccine and drug development. How the structure dynamics of the full-length spikes incorporated in viral lipid envelope correlates wi...
Autores principales: | Chmielewski, David, Wilson, Eric A., Pintilie, Grigore, Zhao, Peng, Chen, Muyuan, Schmid, Michael F., Simmons, Graham, Wells, Lance, Jin, Jing, Singharoy, Abhishek, Chiu, Wah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630519/ https://www.ncbi.nlm.nih.gov/pubmed/37935678 http://dx.doi.org/10.1038/s41467-023-42836-9 |
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