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Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism

Previously, we and others reported a rapid and dramatic increase in brain prostanoids (PG), including prostaglandins, prostacyclins, and thromboxanes, under ischemia that is traditionally explained through the activation of esterified arachidonic acid (20:4n6) release by phospholipases as a substrat...

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Detalles Bibliográficos
Autores principales: Seeger, Drew R., Schofield, Brennon, Besch, Derek, Golovko, Svetlana A., Kotha, Peddanna, Parmer, Meredith, Solaymani-Mohammadi, Shahram, Golovko, Mikhail Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630775/
https://www.ncbi.nlm.nih.gov/pubmed/37783389
http://dx.doi.org/10.1016/j.jlr.2023.100452