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Enhancing the anticancer potential of metformin: fabrication of efficient nanospanlastics, in vitro cytotoxic studies on HEP-2 cells and reactome enhanced pathway analysis

Metformin (MET), an oral antidiabetic drug, was reported to possess promising anticancer effects. We hypothesized that MET encapsulation in unique nanospanlastics would enhance its anticancer potential against HEP-2 cells. Our results showed the successful fabrication of Nano-MET spanlastics (d = 23...

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Detalles Bibliográficos
Autores principales: Raafat, Shereen Nader, El Wahed, Sara Abd, Badawi, Noha M., Saber, Mona M., Abdollah, Maha R.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630776/
https://www.ncbi.nlm.nih.gov/pubmed/38024451
http://dx.doi.org/10.1016/j.ijpx.2023.100215