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Transfixed by transgenics: how pathology assumptions are slowing progress in Alzheimer's disease and related dementia research

Model organisms of human diseases are invaluable tools for unraveling pathogenic mechanisms, identifying potential targets for drug development, and evaluating the therapeutic efficacy of candidates in preclinical trials. The utility of model organisms hinges upon their ability to faithfully replica...

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Detalles Bibliográficos
Autor principal: D'Adamio, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630870/
https://www.ncbi.nlm.nih.gov/pubmed/37750482
http://dx.doi.org/10.15252/emmm.202318479