Intratumoral co‐injection of NK cells and NKG2A‐neutralizing monoclonal antibodies

NK‐cell reactivity against cancer is conceivably suppressed in the tumor microenvironment by the interaction of the inhibitory receptor NKG2A with the non‐classical MHC‐I molecules HLA‐E in humans or Qa‐1(b) in mice. We found that intratumoral delivery of NK cells attains significant therapeutic eff...

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Detalles Bibliográficos
Autores principales: Melero, Ignacio, Ochoa, Maria C, Molina, Carmen, Sanchez‐Gregorio, Sandra, Garasa, Saray, Luri‐Rey, Carlos, Hervas‐Stubbs, Sandra, Casares, Noelia, Elizalde, Edurne, Gomis, Gabriel, Cirella, Assunta, Berraondo, Pedro, Teijeira, Alvaro, Alvarez, Maite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630884/
https://www.ncbi.nlm.nih.gov/pubmed/37782273
http://dx.doi.org/10.15252/emmm.202317804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630884/
https://www.ncbi.nlm.nih.gov/pubmed/37782273
http://dx.doi.org/10.15252/emmm.202317804

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