NRF3 suppresses squamous carcinogenesis, involving the unfolded protein response regulator HSPA5

Epithelial skin cancers are extremely common, but the mechanisms underlying their malignant progression are still poorly defined. Here, we identify the NRF3 transcription factor as a tumor suppressor in the skin. NRF3 protein expression is strongly downregulated or even absent in invasively growing...

Descripción completa

Detalles Bibliográficos
Autores principales: Gurri, Selina, Siegenthaler, Beat, Cangkrama, Michael, Restivo, Gaetana, Huber, Marcel, Saliba, James, Dummer, Reinhard, Blank, Volker, Hohl, Daniel, Werner, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630885/
https://www.ncbi.nlm.nih.gov/pubmed/37807968
http://dx.doi.org/10.15252/emmm.202317761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630885/
https://www.ncbi.nlm.nih.gov/pubmed/37807968
http://dx.doi.org/10.15252/emmm.202317761

Ejemplares similares