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Hierarchy of the Components in Spray-Dried, Protein-Excipient Particles Using DNP-Enhanced NMR Spectroscopy

[Image: see text] Protein-based drugs are becoming increasingly important, but there are challenges associated with their formulation (for example, formulating stable inhalable aerosols while maintaining the proper long-term stability of the protein). Determining the morphology of multicomponent, pr...

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Detalles Bibliográficos
Autores principales: Berruyer, Pierrick, Lindkvist, Maria, Gracin, Sandra, Starciuc, Tatiana, Bertarello, Andrea, Busi, Baptiste, Schantz, Staffan, Emsley, Lyndon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630941/
https://www.ncbi.nlm.nih.gov/pubmed/37782000
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00539