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Effective Treatment of SSTR2-Positive Small Cell Lung Cancer Using (211)At-Containing Targeted α-Particle Therapy Agent Which Promotes Endogenous Antitumor Immune Response

[Image: see text] Small cell lung cancer (SCLC) is a neuroendocrine tumor with a high degree of malignancy. Due to limited treatment options, patients with SCLC have a poor prognosis. We have found, however, that intravenously administered octreotide (Oct) armed with astatine-211 ([(211)At]SAB-Oct)...

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Detalles Bibliográficos
Autores principales: Qin, Shanshan, Yang, Yuanyou, Zhang, Jiajia, Yin, Yuzhen, Liu, Weihao, Zhang, Han, Fan, Xin, Yang, Mengdie, Yu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630944/
https://www.ncbi.nlm.nih.gov/pubmed/37788300
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00427