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Desolvation Processes in Channel Solvates of Niclosamide

[Image: see text] The antiparasitic drug niclosamide (NCL) is notable for its ability to crystallize in multiple 1:1 channel solvate forms, none of which are isostructural. Here, using a combination of time-resolved synchrotron powder X-ray diffraction and thermogravimetry, the process-induced desol...

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Detalles Bibliográficos
Autores principales: Mann, Jen E., Gao, Renee, London, Shae S., Swift, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630950/
https://www.ncbi.nlm.nih.gov/pubmed/37850910
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00481