An aza-Robinson Annulation Strategy for the Synthesis of Fused Bicyclic Amides: Synthesis of (±)-Coniceine and Quinolizidine

[Image: see text] An aza-Robinson annulation strategy is described using a NaOEt-catalyzed conjugate addition of cyclic imides onto vinyl ketones, followed by a TfOH-mediated intramolecular aldol condensation to afford densely functionalized fused bicyclic amides. The potential use of these amides i...

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Detalles Bibliográficos
Autores principales: Garay-Talero, Alexander, Goulart, Tales A. C., Gallo, Rafael D. C., Pinheiro, Roberto do C., Hoyos-Orozco, Catalina, Jurberg, Igor D., Gamba-Sánchez, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630962/
https://www.ncbi.nlm.nih.gov/pubmed/37877616
http://dx.doi.org/10.1021/acs.orglett.3c02798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630962/
https://www.ncbi.nlm.nih.gov/pubmed/37877616
http://dx.doi.org/10.1021/acs.orglett.3c02798

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