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An aza-Robinson Annulation Strategy for the Synthesis of Fused Bicyclic Amides: Synthesis of (±)-Coniceine and Quinolizidine

[Image: see text] An aza-Robinson annulation strategy is described using a NaOEt-catalyzed conjugate addition of cyclic imides onto vinyl ketones, followed by a TfOH-mediated intramolecular aldol condensation to afford densely functionalized fused bicyclic amides. The potential use of these amides i...

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Detalles Bibliográficos
Autores principales:	Garay-Talero, Alexander, Goulart, Tales A. C., Gallo, Rafael D. C., Pinheiro, Roberto do C., Hoyos-Orozco, Catalina, Jurberg, Igor D., Gamba-Sánchez, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10630962/ https://www.ncbi.nlm.nih.gov/pubmed/37877616 http://dx.doi.org/10.1021/acs.orglett.3c02798

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