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Age-related promoter-switch regulates Runx1 expression in adult rat hearts

BACKGROUND: Runt-related transcription factor-1 (RUNX1), a key member of the core-binding factor family of transcription factors, has emerged as a novel therapeutic target for cardiovascular disease. There is an urgent need to fully understand the expression pattern of Runx1 in the heart and the mec...

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Detalles Bibliográficos
Autores principales: Song, Jiawei, Zhang, Xiaoling, Lv, Sinan, Liu, Meng, Hua, Xing, Yue, Limin, Wang, Si, He, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631011/
https://www.ncbi.nlm.nih.gov/pubmed/37936072
http://dx.doi.org/10.1186/s12872-023-03583-3