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Early detection of hepatocellular carcinoma via no end-repair enzymatic methylation sequencing of cell-free DNA and pre-trained neural network

BACKGROUND: Early detection of hepatocellular carcinoma (HCC) is important in order to improve patient prognosis and survival rate. Methylation sequencing combined with neural networks to identify cell-free DNA (cfDNA) carrying aberrant methylation offers an appealing and non-invasive approach for H...

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Detalles Bibliográficos
Autores principales: Deng, Zhenzhong, Ji, Yongkun, Han, Bing, Tan, Zhongming, Ren, Yuqi, Gao, Jinghan, Chen, Nan, Ma, Cong, Zhang, Yichi, Yao, Yunhai, Lu, Hong, Huang, Heqing, Xu, Midie, Chen, Lei, Zheng, Leizhen, Gu, Jianchun, Xiong, Deyi, Zhao, Jianxin, Gu, Jinyang, Chen, Zutao, Wang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631027/
https://www.ncbi.nlm.nih.gov/pubmed/37936230
http://dx.doi.org/10.1186/s13073-023-01238-8