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Role of macrophage-to-myofibroblast transition in chronic liver injury and liver fibrosis

BACKGROUND: Chronic liver injury contributes to liver fibrosis, which is characterized by the excessive deposition of extracellular matrix (ECM) components. ECM is mainly composed of myofibroblasts. Recently, macrophage-to-myofibroblasts transition (MMT), has been identified as a novel origin for my...

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Detalles Bibliográficos
Autores principales: Xia, Suhong, Huang, Yujie, Zhang, Yu, Zhang, Mingyu, Zhao, Kai, Han, Ping, Tian, Dean, Liao, Jiazhi, Liu, Jingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631085/
https://www.ncbi.nlm.nih.gov/pubmed/37941043
http://dx.doi.org/10.1186/s40001-023-01488-7