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Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties

BACKGROUND: Intravitreal injection (IVI) of antibody biologics is a key treatment approach in ophthalmology. Pharmaceutical compounding and storage of prefilled syringes for IVI must take place without impairing the structure and function of the biologics. This study investigated the effect of withd...

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Detalles Bibliográficos
Autores principales: Jørstad, Øystein Kalsnes, Foss, Stian, Gjølberg, Torleif Tollefsrud, Mester, Simone, Nyquist-Andersen, Mari, Sivertsen, Magne Sand, Fossum, Dag, Gleditsch, Espen, Moe, Morten Carstens, Andersen, Jan Terje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631190/
https://www.ncbi.nlm.nih.gov/pubmed/37936232
http://dx.doi.org/10.1186/s40942-023-00507-3