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Muc2 mucin o-glycosylation interacts with enteropathogenic Escherichia coli to influence the development of ulcerative colitis based on the NF-kB signaling pathway

BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine characterized by a compromised intestinal epithelial barrier. Mucin glycans are crucial in preserving barrier function during bacterial infections, although the underlying mechanisms remain largely unexplored. MET...

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Detalles Bibliográficos
Autores principales: Wei, Juan, Chen, Chunyan, Feng, Jing, Zhou, Shuping, Feng, Xiaoyue, Yang, Zhao, Lu, Heng, Tao, Hui, Li, Liuying, Xv, Huabing, Xuan, Ji, Wang, Fangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631195/
https://www.ncbi.nlm.nih.gov/pubmed/37940996
http://dx.doi.org/10.1186/s12967-023-04687-2