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Hypoxic tumor cell-derived small extracellular vesicle miR-152-3p promotes cervical cancer radioresistance through KLF15 protein

BACKGROUND: Radiotherapy is widely used in treating cervical cancer patients, however, radioresistance unavoidably occurs and seriously affects the treatment effect. It is well known that hypoxia plays an important role in promoting radioresistance in tumor microenvironment, yet our understanding of...

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Detalles Bibliográficos
Autores principales: Zhou, Junying, Lei, Ningjing, Tian, Wanjia, Guo, Ruixia, Gao, Feng, Fu, Hanlin, Zhang, Jing, Dong, Shiliang, Chen, Mengyu, Ma, Qian, Li, Yong, Chang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631204/
https://www.ncbi.nlm.nih.gov/pubmed/37936130
http://dx.doi.org/10.1186/s13014-023-02369-3