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MicroRNA-584-5p/RUNX family transcription factor 2 axis mediates hypoxia-induced osteogenic differentiation of periosteal stem cells

BACKGROUND: The hypoxic environment during bone healing is important in regulating the differentiation of periosteal stem cells (PSCs) into osteoblasts or chondrocytes; however, the underlying mechanisms remain unclear. AIM: To determine the effect of hypoxia on PSCs, and the expression of microRNA-...

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Detalles Bibliográficos
Autores principales: Lu, Jia-Jia, Shi, Xiao-Jian, Fu, Qiang, Li, Yong-Chuan, Zhu, Lei, Lu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631372/
https://www.ncbi.nlm.nih.gov/pubmed/37970237
http://dx.doi.org/10.4252/wjsc.v15.i10.979