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Organocatalytic atroposelective synthesis of axially chiral N,N′-pyrrolylindoles via de novo indole formation

The first organocatalytic atroposelective synthesis of axially chiral N,N′-pyrrolylindoles based on o-alkynylanilines was successfully established via de novo indole formation catalyzed by chiral phosphoric acid (CPA). This new synthetic strategy introduced CPA-catalyzed asymmetric 5-endo-dig cycliz...

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Detalles Bibliográficos
Autores principales: Wang, Cong-Shuai, Xiong, Qi, Xu, Hui, Yang, Hao-Ran, Dang, Yanfeng, Dong, Xiu-Qin, Wang, Chun-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631393/
https://www.ncbi.nlm.nih.gov/pubmed/37969599
http://dx.doi.org/10.1039/d3sc03686c