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Targeting histone deacetylase suppresses tumor growth through eliciting METTL14‐modified m(6)A RNA methylation in ocular melanoma

BACKGROUND: Diversified histone deacetylation inhibitors (HDACis) have demonstrated encouraging outcomes in multiple malignancies. N6‐methyladenine (m(6)A) is the most prevalent messenger RNA modification that plays an essential role in the regulation of tumorigenesis. Howbeit, an in‐depth understan...

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Detalles Bibliográficos
Autores principales: Zhuang, Ai, Gu, Xiang, Ge, Tongxin, Wang, Shaoyun, Ge, Shengfang, Chai, Peiwei, Jia, Renbing, Fan, Xianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631484/
https://www.ncbi.nlm.nih.gov/pubmed/37466203
http://dx.doi.org/10.1002/cac2.12471