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Interactions of Indoleamine 2,3‐dioxygenase‐expressing LAMP3(+) dendritic cells with CD4(+) regulatory T cells and CD8(+) exhausted T cells: synergistically remodeling of the immunosuppressive microenvironment in cervical cancer and therapeutic implications

BACKGROUND: Cervical cancer (CC) is the fourth most common cancer in women worldwide. Although immunotherapy has been applied in clinical practice, its therapeutic efficacy remains far from satisfactory, necessitating further investigation of the mechanism of CC immune remodeling and exploration of...

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Detalles Bibliográficos
Autores principales: Qu, Xinyu, Wang, Yumeng, Jiang, Qian, Ren, Tingting, Guo, Chenyan, Hua, Keqin, Qiu, Junjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631485/
https://www.ncbi.nlm.nih.gov/pubmed/37794698
http://dx.doi.org/10.1002/cac2.12486