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Mukaiyama aldol reaction: an effective asymmetric approach to access chiral natural products and their derivatives/analogues

The Mukaiyama aldol reaction is generally a Lewis-acid catalyzed cross-aldol reaction between an aldehyde or ketone and silyl enol ether. It was first described by Mukaiyama in 1973, almost 5 decades ago, to achieve the enantioselective synthesis of β-hydroxy carbonyl compounds in high percentage yi...

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Detalles Bibliográficos
Autores principales: Mushtaq, Aqsa, Zahoor, Ameer Fawad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631541/
https://www.ncbi.nlm.nih.gov/pubmed/38025859
http://dx.doi.org/10.1039/d3ra05058k