FAT10 is phosphorylated by IKKβ to inhibit the antiviral type-I interferon response

IFN-I secretion provides a rapid host defense against infection with RNA viruses. Within the host cell, viral RNA triggers the activation of the RIG-I signaling pathway, leading to the production of IFN-I. Because an exaggerated IFN-I response causes severe tissue damage, RIG-I signaling is tightly...

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Detalles Bibliográficos
Autores principales: Saxena, Kritika, Roverato, Nicola Domenico, Reithmann, Melody, Mah, Mei Min, Schregle, Richard, Schmidtke, Gunter, Silbern, Ivan, Urlaub, Henning, Aichem, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631552/
https://www.ncbi.nlm.nih.gov/pubmed/37940187
http://dx.doi.org/10.26508/lsa.202101282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631552/
https://www.ncbi.nlm.nih.gov/pubmed/37940187
http://dx.doi.org/10.26508/lsa.202101282

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