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Periostin is overexpressed, correlated with fibrosis and differs among grades of cardiomyocyte hypertrophy in myectomy tissue of patients with hypertrophic cardiomyopathy

Periostin, a secreted matricellular protein, has been implicated in cardiac extracellular matrix remodeling and fibrosis. Evidence suggest that periostin stimulates cardiomyocyte hypertrophy. The current study aims to investigate the extent of periostin expression in patients with advanced Hypertrop...

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Detalles Bibliográficos
Autores principales: Ioakeimidis, Nikolaos S., Pitsis, Antonios, Zegkos, Thomas, Ntelios, Dimitrios, Kelpis, Timotheos, Papamitsou, Theodora, Parcharidou, Despoina, Gossios, Thomas, Efthimiadis, Georgios, Meditskou, Soultana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631645/
https://www.ncbi.nlm.nih.gov/pubmed/37939043
http://dx.doi.org/10.1371/journal.pone.0293427