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The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1

The chemical modification of RNA bases represents a ubiquitous activity that spans all domains of life. Pseudouridylation is the most common RNA modification and is observed within tRNA, rRNA, ncRNA and mRNAs. Pseudouridine synthase or ‘PUS’ enzymes include those that rely on guide RNA molecules and...

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Detalles Bibliográficos
Autores principales: Grünberg, Sebastian, Doyle, Lindsey A., Wolf, Eric J., Dai, Nan, Corrêa, Ivan R., Yigit, Erbay, Stoddard, Barry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631681/
https://www.ncbi.nlm.nih.gov/pubmed/37939088
http://dx.doi.org/10.1371/journal.pone.0291267