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Deep-learning–assisted Sort-Seq enables high-throughput profiling of gene expression characteristics with high precision

Owing to the nondeterministic and nonlinear nature of gene expression, the steady-state intracellular protein abundance of a clonal population forms a distribution. The characteristics of this distribution, including expression strength and noise, are closely related to cellular behavior. However, q...

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Detalles Bibliográficos
Autores principales: Feng, Huibao, Li, Fan, Wang, Tianmin, Xing, Xin-hui, Zeng, An-ping, Zhang, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631719/
https://www.ncbi.nlm.nih.gov/pubmed/37939173
http://dx.doi.org/10.1126/sciadv.adg5296