Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus

The development and diversity of neuronal subtypes in the human hypothalamus has been insufficiently characterized. To address this, we integrated transcriptomic data from 241,096 cells (126,840 newly generated) in the prenatal and adult human hypothalamus to reveal a temporal trajectory from prolif...

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Detalles Bibliográficos
Autores principales: Herb, Brian R., Glover, Hannah J., Bhaduri, Aparna, Colantuoni, Carlo, Bale, Tracy L., Siletti, Kimberly, Hodge, Rebecca, Lein, Ed, Kriegstein, Arnold R., Doege, Claudia A., Ament, Seth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631741/
https://www.ncbi.nlm.nih.gov/pubmed/37939194
http://dx.doi.org/10.1126/sciadv.adf6251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631741/
https://www.ncbi.nlm.nih.gov/pubmed/37939194
http://dx.doi.org/10.1126/sciadv.adf6251

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