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Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus
The development and diversity of neuronal subtypes in the human hypothalamus has been insufficiently characterized. To address this, we integrated transcriptomic data from 241,096 cells (126,840 newly generated) in the prenatal and adult human hypothalamus to reveal a temporal trajectory from prolif...
Autores principales: | Herb, Brian R., Glover, Hannah J., Bhaduri, Aparna, Colantuoni, Carlo, Bale, Tracy L., Siletti, Kimberly, Hodge, Rebecca, Lein, Ed, Kriegstein, Arnold R., Doege, Claudia A., Ament, Seth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631741/ https://www.ncbi.nlm.nih.gov/pubmed/37939194 http://dx.doi.org/10.1126/sciadv.adf6251 |
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