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Conserved biophysical compatibility among the highly variable germline-encoded regions shapes TCR-MHC interactions
T cells are critically important components of the adaptive immune system primarily responsible for identifying and responding to pathogenic challenges. This recognition of pathogens is driven by the interaction between membrane-bound T cell receptors (TCRs) and antigenic peptides presented on major...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631762/ https://www.ncbi.nlm.nih.gov/pubmed/37861280 http://dx.doi.org/10.7554/eLife.90681 |