MEK/ERK and PI3K/AKT pathway inhibitors affect the transformation of myelodysplastic syndrome into acute myeloid leukemia via H3K27me3 methylases and de-methylases

The transformation of myelodysplastic syndrome (MDS) into acute myeloid leukemia (AML) poses a significant clinical challenge. The trimethylation of H3 on lysine 27 (H3K27me3) methylase and de-methylase pathway is involved in the regulation of MDS progression. The present study investigated the func...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Zhuanzhen, Chen, Xiuhua, Zhang, Yaofang, Ren, Fanggang, Ma, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631768/
https://www.ncbi.nlm.nih.gov/pubmed/37921060
http://dx.doi.org/10.3892/ijo.2023.5588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631768/
https://www.ncbi.nlm.nih.gov/pubmed/37921060
http://dx.doi.org/10.3892/ijo.2023.5588

Ejemplares similares