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Single-cell RNA sequencing of murine ankle joints over time reveals distinct transcriptional changes following Borrelia burgdorferi infection

Lyme disease is caused by the bacterial pathogen Borrelia burgdorferi, which can be readily modeled in laboratory mice. In order to understand the cellular and transcriptional changes that occur during B. burgdorferi infection, we conducted single-cell RNA sequencing (scRNA-seq) of ankle joints of i...

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Detalles Bibliográficos
Autores principales: Helble, Jennifer D., Walsh, Michael J., McCarthy, Julie E., Smith, Neal P., Tirard, Alice J., Arnold, Benjamin Y., Villani, Alexandra-Chloe, Hu, Linden T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632114/
https://www.ncbi.nlm.nih.gov/pubmed/37953958
http://dx.doi.org/10.1016/j.isci.2023.108217