Precise identification of cell states altered in disease using healthy single-cell references

Joint analysis of single-cell genomics data from diseased tissues and a healthy reference can reveal altered cell states. We investigate whether integrated collections of data from healthy individuals (cell atlases) are suitable references for disease-state identification and whether matched control...

Descripción completa

Detalles Bibliográficos
Autores principales: Dann, Emma, Cujba, Ana-Maria, Oliver, Amanda J., Meyer, Kerstin B., Teichmann, Sarah A., Marioni, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632138/
https://www.ncbi.nlm.nih.gov/pubmed/37828140
http://dx.doi.org/10.1038/s41588-023-01523-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632138/
https://www.ncbi.nlm.nih.gov/pubmed/37828140
http://dx.doi.org/10.1038/s41588-023-01523-7

Ejemplares similares