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Precise identification of cell states altered in disease using healthy single-cell references
Joint analysis of single-cell genomics data from diseased tissues and a healthy reference can reveal altered cell states. We investigate whether integrated collections of data from healthy individuals (cell atlases) are suitable references for disease-state identification and whether matched control...
Autores principales: | Dann, Emma, Cujba, Ana-Maria, Oliver, Amanda J., Meyer, Kerstin B., Teichmann, Sarah A., Marioni, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632138/ https://www.ncbi.nlm.nih.gov/pubmed/37828140 http://dx.doi.org/10.1038/s41588-023-01523-7 |
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