Age-dependent topic modeling of comorbidities in UK Biobank identifies disease subtypes with differential genetic risk

The analysis of longitudinal data from electronic health records (EHRs) has the potential to improve clinical diagnoses and enable personalized medicine, motivating efforts to identify disease subtypes from patient comorbidity information. Here we introduce an age-dependent topic modeling (ATM) meth...

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Detalles Bibliográficos
Autores principales: Jiang, Xilin, Zhang, Martin Jinye, Zhang, Yidong, Durvasula, Arun, Inouye, Michael, Holmes, Chris, Price, Alkes L., McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632146/
https://www.ncbi.nlm.nih.gov/pubmed/37814053
http://dx.doi.org/10.1038/s41588-023-01522-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632146/
https://www.ncbi.nlm.nih.gov/pubmed/37814053
http://dx.doi.org/10.1038/s41588-023-01522-8

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