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Predictions of DNA mechanical properties at a genomic scale reveal potentially new functional roles of DNA flexibility
Mechanical properties of DNA have been implied to influence many of its biological functions. Recently, a new high-throughput method, called loop-seq, which allows measuring the intrinsic bendability of DNA fragments, has been developed. Using loop-seq data, we created a deep learning model to explo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632188/ https://www.ncbi.nlm.nih.gov/pubmed/37954573 http://dx.doi.org/10.1093/nargab/lqad097 |