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Predictions of DNA mechanical properties at a genomic scale reveal potentially new functional roles of DNA flexibility

Mechanical properties of DNA have been implied to influence many of its biological functions. Recently, a new high-throughput method, called loop-seq, which allows measuring the intrinsic bendability of DNA fragments, has been developed. Using loop-seq data, we created a deep learning model to explo...

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Detalles Bibliográficos
Autores principales: Back, Georg, Walther, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632188/
https://www.ncbi.nlm.nih.gov/pubmed/37954573
http://dx.doi.org/10.1093/nargab/lqad097